https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42351 Wed 30 Aug 2023 15:15:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45051 Wed 26 Oct 2022 11:42:57 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33708 Wed 09 Mar 2022 16:03:21 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55864 Tue 02 Jul 2024 16:27:52 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29916 Thu 27 Jan 2022 15:56:37 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27846 90, 60-90, and <60 mL/min/1.73 m², respectively). Outcomes: The effect of admission eGFR on the primary outcome of death or major disability at 90 days (defined as modified Rankin Scale scores of 3-6) was analyzed using a multivariable logistic regression model. Potential effect modification of intensive BP lowering treatment by admission eGFR was assessed by interaction terms. Results: Of 2,623 included participants, 912 (35%) and 280 (11%) had mildly and moderately/severely decreased eGFRs, respectively. Patients with moderately/severely decreased eGFRs had the greatest risk for death or major disability at 90 days (adjusted OR, 1.82; 95% CI, 1.28-2.61). Effects of early intensive BP lowering were consistent across different eGFRs (P = 0.5 for homogeneity). Limitations: Generalizability issues arising from a clinical trial population. Conclusions: Decreased eGFR predicts poor outcome in acute ICH. Early intensive BP lowering provides similar treatment effects in patients with ICH with decreased eGFRs.]]> Thu 09 Dec 2021 11:03:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7363 Sat 24 Mar 2018 08:40:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22700 a) with the effect of CVVHDF modeled as a time-dependent covariate. This suggested that there was initially good clearance with CVVHDF (4 times endogenous clearance), which rapidly declined within hours.]]> Sat 24 Mar 2018 07:15:25 AEDT ]]>